𝗖𝗵𝗶𝗰𝗸𝗲𝗻 𝗮𝗻𝗮𝘁𝗼𝗺𝘆: 𝗕𝗹𝗼𝗼𝗱 𝗰𝗼𝗺𝗽𝗼𝘀𝗶𝘁𝗶𝗼𝗻
Blood is the transport vehicle for the body. It carries, among other things: Products of metabolism, Hormones, enzymes, antibodies, effete products of tissues and organs and many other inorganic and organic substances.
Erythrocytes:
These are large, flat, oval, nucleated cells. The nucleus is positioned in the centre of the cell, and are typically elongated. Occasionally, they will not contain a nucleus (like mammalian erythrocytes), but these are atypical. The red colouring is caused by the presence of haemoglobin, which binds to oxygen. Their function is to transport oxygen to tissues and organs. They are formed in the red bone marrow.
Leucocytes:
They are nucleated cells with a colourless cytoplasm. Some have fine granules in their cytoplasms, while others have coarse granules, and others have no granules. Granulocytes are a type of leucocytes. Most are phagocytic. Their shape is therefore variable, but they are circular in normal conditions. They are mono-nuclear and the nucleus is often multi-lobed. They are formed in the spleen, lymphoid tissue and bone marrow. Types of leucocytes are:
Heterophils are spherical in shape, and their nuclei are distinctly lobed, with thick strands of nuclear material (nucleoplasm) joining them. They are important for protection against bacterial infections, as they have a bactericide function, and ingest protein.
Eosinophils have bi-lobed nuclei. There contain fewer, rounder granules than in heterophils. The function is unknown, but their numbers increase in cases of internal parasitic infections. It has also been suggested they have a detoxification function.
Basophils have a generally oval shaped nucleus that is not lobed. There are fewer of these, and their function is unknown.
Lymphocytes are the most common heterophils. Their size varies, though older cells tend to be smaller. The nucleus size is the same, and may be kidney-shaped. The mobility of these cells is reduced, and they likely have zero phagocytic action. Their function is to regulate toxic materials. They also release enzymes that assist in the synthesis of the nucleoplasm.
Monocytes are the largest leucocytes and are sometimes difficult to distinguish from lymphocytes. The nucleus varies in shape. They are very mobile and phagocytic. Their function is to remove, by ingestion, bacteria, protozoan and tissue debris.
Thrombocytes are similar to platelets (found in mammals), but are less involved in blood clotting. They are numerous, and the smallest of all blood cells, and group together in clumps. They are formed in the bone marrow.
Plasma:
Plasma is the liquid, non-cellular part of the blood. It contains: Glucose, non-protein nitrogen substances, plasma proteins, plasma liquids, plasma enzymes, metallic elements, water.
Blood glucose:
As in mammals, it is in the form of D-glucose, although it is usually at higher levels. Hormones like glucagon, insulin, corticoids and glucocorticoids affect the level. Plane of nutrition also affects levels. The average level is about 10mmol/litre (compared to around 4.5mmol/ litre in humans).
Non-protein nitrogen:
After the removal of plasma proteins, the remaining fluid contains a number of nitrogenous substances including: Uric acid, urea, creatine, free amino acids, free ammonia.
Uric acid represent the bulk of waste nitrogen. They are the end product of protein metabolism. The level is influenced by sex and reproductive state (non-layers have higher levels). Urea is eliminated by the kidney, and is influenced by age and sex.
Creatine is an amino acid present in animal tissues. It combines with phosphate (making phosphocreatine) which is important in the anaerobic phase of muscle contraction. The ammonium ions are found in very small quantities. Around 22 amino acids have been found in small quantities in avian blood (although not all at the same time).
Plasma proteins:
Albumins transport calcium and other minerals, fatty acids and hormones.
Immunoglobins are produced by lymphocytes as a result of antigenic demand.
Transferrin transports iron across the intestinal wall. This is part of the secondary immune response, as it makes iron unavailable to viruses and bacteria.
Ceruloplasmin is for copper transport.
Phosvitin carries calcium, iron and phosphate to the yolk and calcium to the shell gland.
Lipoproteins carry fat-soluble vitamins, hormones and some minerals in the blood.
Fibrinogen is important for blood-clotting.