I do have those days, especially when it comes to my chickens/geese. My experience with bumblefoot is in chickens, so not everything may apply. The bigger ones can take a while to heal. So far I've had luck with all of the ones I've dealt with, most of them have been small. There is one girl who had some big bumbles and two weeks ago (more than a month after starting treatment) they were looking pretty good. I need to check her again and see if they're still doing well, probably at bedtime tomorrow. I'm definitely interested to hear how things go with the tricide-neo. This is what I did, and it's kind of gross, so using the spoiler thing: I'd give the foot a good soak/scrub. Spray it with vetericyn, then I'd get to the gross part. The scab had to come off, and lots of the online stuff says to cut into the foot with a scalpel. I wasn't really comfortable digging deep with sharp objects. Instead, I'd use cuticle scissors to get what I could see easily, making sure to get any dead skin (cuts off just like cuticles) and any hard pussy bit that I could. Then I'd spray with vetericyn again really good, and let it dry out a bit. Lots of neosporin and a small piece of gauze got wrapped over the wound and then the chicken was let go. Bowie had this done every second or third day for more than a month because the hard pussy thing was working it's way out. Could someone else have got it in one go, probably, but not me and I can't afford a vet. Bowie never had any issues with it, she continued to lay all through it and I think she really enjoyed the soaks. The other chickens only had to come in for this once or twice before they were improved enough to be done. Most of my chickens handled this really well. The ones who didn't were the skittish ones. There doesn't seem to be any pain in the whole procedure other than when you nick good skin. The good skin bleeds like crazy, but it does stop quickly.