Does any one use ivermectin in chickens ?

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Injectible IS water soluble; pour-on is indeed oil-based. What I have read about overdose is that the most likely complication is blindness (and would require a MASSIVE overdose). Not sure how that would relate to the liver.
 
Quote:
Ivermectin is not labeled for use with poultry. The cattle version states no meat or milk withdrawl so it's reasonable to assume that would also apply to eggs [or at least I find it reasonable]. I've been using the cattle pou on for the last couple of years & it seems to be pretty effective against external parasites. Since I've never had a problem with worms I can't speak to that from experience. Ivermectin was recommended to me by a Vet friend who uses it on his birds.
 
The liver, in any living critter, is what filters out all the toxins from the blood, Ivermectin is considered such a toxin, therefor it can and will damage the liver if an overdose happens, this comes Highly emphasised to me by my poultry vet here, and he also insures me, NO Ivermectin product is water soluble due to the chemical make up used to create it, inject able may look like it is mixing, but it aint... I know there is a product made for pigeons that is water soluble, but it is called IvOmectin, not ImERmectin, as the chemical structure of the wormer was changed to make it water soluble...
 
Just a quick note to those using the ivermectin they get in feed stores, etc, for their domestic pets. Ivermectin is what is in Heartgard, etc. But ivermectin IS a drug, it DOES have side effects at even low percentage strengths, and can be fatal in certain breeds of dogs. For example, ivermectin should NEVER, EVER be used in a collie, sheltie, or collie-or-sheltie cross dog. It almost always (in these breeds) causes neurologic signs, like staggering or seizures, often causes irreversible brain damage, and often causes death.
Just be careful when using a drug in an extra-label manner. Too low a dose might not be effective. Too high a dose might be fatal. Any dose might be fatal in the wrong breed or species (for example, one tylenol is fatal to a cat.) Giving ivermectin to a dog that currently has heartworms (which you can only tell through a blood test) can be fatal.
Just FYI.
 
Just need to correct the misinformation about ivermectin and dog breeds.

While many dogs of the collie breeds have one or more mutant copies of the MDR1 gene, which makes them sensitive to ivermectin and quite a few other drugs, it is NOT true that one must never use ivermectin on dogs of these breeds. Incidence of the mutation is 70% in AKC show-type collies, only 15% in Shetland sheepdogs, and varies among the other collie lineages.

1) The dosages in Heartguard and other commercial heartworm preventatives are too low to cause toxicity, even in mutant/mutant dogs. (But DO NOT economize with home dosing with dogs who have the mutant gene.)

2) There is a relatively inexpensive DNA test for any dog's mutant status. If your dog is on the list of affected breeds, a cross of one of the affected breeds, or a "maybe" of unknown parentage, it's a really good idea to have the test done so you know whether you need to avoid certain drugs or certain dosages before you need it.

List of affected breeds:

http://www.vetmed.wsu.edu/depts-vcpl/breeds.aspx

List of drugs of concern:

http://www.vetmed.wsu.edu/depts-VCPL/drugs.aspx

Two sources for the DNA test:

http://www.vetmed.wsu.edu/depts-VCPL/test.aspx (more expensive)

http://www.animalgenetics.us/ (cheaper, not listed on their website, click "contact us" and ask about the MDR1 test)

Ivomec is neither water nor oil-soluble. The acceptable dilutant is glycerol.
 
Ivomec is ivermectin sitting in glycerol, so you can use one of the glycerols (PG or similar) to dilute it, but you can also use anything thick enough to hold it in suspension long enough to dose it orally. Lots of people use a thick vegetable oil or karo syrup or similar.

People are STUPID about ivomec in dogs. They figure it's a 1% solution, right? So that means it's gentle? How about I give a cc or two to my dog - more is better than less! And they kill their collie.

NO. One-TENTH of a ml of straight ivomec 1% treats 100 lb for heartworm prevention. It's not even a fifth of a drop. I can do my entire herd of dogs using a tiny insulin syringe that I fill 1/10 with ivomec, 9/10 with karo, mix like crazy, dose 1/10 per 10 lb. That amount is safe for any breed, mutated gene or no.

Bringing it back to chickens, the research I can find says ivermectin is not great at curing intestinal worms in chickens until you get to a dose very high to their toxic level. It should be more effective on the skin but I don't know that there's an established dosage even off-label. If the problem is worms, you seem to be better off using fenbendazole. If you have mites and don't want to use ivermectin spinosad spray (sold as an organic pesticide in a lot of garden shops) is not only very effective but has a residual protection of at least three weeks . You'd spray the coop/roosts to the point of dripping (that's the dosage that was tested - spray to the point of runoff), not the birds themselves.

Joanna Kimball
blacksheepcardigans.com
 
Sure: Here it is as an injectable/oral against worms: http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0450.1989.tb00635.x/abstract

Here it is injected against mites: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TD7-476MPXM-T1&_user=10&_origUdi=B6TD7-50FGYD7-1&_fmt=high&_coverDate=01/31/1987&_rdoc=1&_orig=article&_origin=article&_zone=related_art&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=b299f2d2910cb5c5091457ff2ef8117a

An interesting one showing that ivermectin DOES show up in eggs after dosing: http://www.euroresidue.nl/ER_IV/Contributions%20I-Z/keukens%20678-682.PDF

Ivermectin is one of the most studied meds out there and several companies use it as a cash cow; they would LOVE IT if it worked in chickens because they would open up a whole new market. The fact that there are no label directions for poultry (and no formulations for poultry) are not because it hasn't been tried but because they think it doesn't work well enough to market it.

There's a great (free) e-book put out by the World Health Organization specifically about poultry parasites, including how to figure out what you're dealing with using tabletop techniques (i.e., what you have around, plus a cheap microscope): http://www.smallstock.info/reference/KVLDK/Poultry_Parasites.pdf ; it (unsurprisingly) tells smallholders to rotate the -zoles and piperazine, which is exactly what most on this board will recommend.

Joanna Kimball
blacksheepcardigans.com
 
Most poultry dose info for Ivermectin on this board seems to be the pour-on, applied to the skin on the back of the bird's neck. The dosages are apparently largely experiential -- what has worked (and not harmed) for worming and skin parasites. To wit: 1-2 small drops (from a syringe or fine-tipped pipette) for the smallest bantams (e.g. 1 drop for OEG bantam hens and Seramas of both sexes, 2 drops for OEG bantam roosters), 3 drops for average-size bantams, 4 drops for medium standard chickens, 5 drops for the largest breeds.

In my own experience, I've found that the above dosages do no harm to the birds and in fact do kill lice. Northern fowl mites, not so much. And I don't know whether the Ivermectin is effectively worming the flock, to be frank. I have been using Piperazine, which definitely does work but needs to be followed up with a second dose in 2 weeks.

fwiw
 

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