Might be a good question for your vet, too. Our dog needs a tranquilizer for long car rides due to anxiety. Our vet prescribed us one.She stands up from a dead "sleep" suddenly and then it's all over. Doesn't matter if I stop the car or anything. I read dogs can have non-drowsy Dramamine and may try it. We have a 30+ minute car ride on Saturday to the vet for next shots... Gonna paper the car in puppy pads... That'll at least help me understand if it's anxiety or motion.