My problem with most of those kind of meds is they rip my stomach to shreds. I have the bowel spasms & bad bladder spasms. Have tried so many meds & they all have worse side effects than what they are treating. I am one of those patients that no doctors want. If something is going to go wrong , it will, if it has bad side effects, they always bother me. If a doctor can't figure out the problem, I'm that patient & it usually takes a lot of suffering and a 2-3 year time frame before they figure it out.