Had a co-worker for a while with Asperger's. This was not a personality quirk that no one other than a family member or spouse would realize--you knew it instantly, after talking to her for all of 15 seconds. This was not just saying hurtful things; Laura never said hurtful things, she was very kind and helpful to people and generally a good and well-meaning person. She was not really what anyone would consider "high-functioning," either, her flat affect was quite severe and made it difficult for her to communicate and understand the corporate culture. Yet she was a brilliant analytical chemist, and certainly managed to hold down a job, lived on her own, had many hobbies, wrote music critiques for the local entertainment magazine.
Please don't label your spouse/friend/relative as being autistic or on the autism spectrum simply because they have a quirky, odd personality, unusual interests or hobbies, or you just don't "click" with them personality-wise. Certainly don't excuse nasty behaviors on the grounds that the person has Asperger's! Like anyone else, Aspies might be nice people or nasty people and the Asperger's has nothing to do with that.
I think it's really terrible for people who are genuinely autistic and have Asperger's that the diagnosis is being abused to mean "anyone who isn't getting along with others right at the moment." There have been many studies showing that there really is NO increase in the number of autistic people that cannot be explained by changes in diagnostic criteria. Some people have terrible personalities for other reasons, and it has nothing to do with whether or not they are autistic. Being a jerk is not a neurological disorder.