Interesting. Thank you for looking it up, TimSuze,
Latest research says the frizzle gene does not directly effect metabolism and indicates the health issues may be related to heat loss. The research also suggested the syndrome may be pleotropic. If the health issues are due to heat loss then the recessive gene should take care of the problem ( substantially reduce heat loss). Frizzled birds that live in warm climates should be less effected than those living in milder climates.
If the gene's effect is pleotropic, a study would have to be carried out to determine the answer to your question. Does the recessive modifier of frizzle negate the health issues?
Tim
I assume heat loss is from broken feathers, whose absence prevents them from insulating the bird. My sizzles seem really well-feathered, and I've never noticed any particular fragility to them; but I also live in a relatively warm climate. I've never had more than a few frizzled birds; right now one sizzle hen and one frizzled silkie hen who are both penned, and two sizzle roosters who roam the yard, and do not have access to the frizzled hens. I don't believe the frizzled silkie is homozygous, but her feathers do tend to have stiff shafts, and break fairly easily; they only curl a little. The sizzle has soft shafts, the feathers curl much more (typical heterozygous appearance) and are very full.
If pleiotropic, then it seems that health issues might be negated by removing one of the necessary genes, as well as the possibility of the modifier reducing any affect. I don't suppose there is likely to be a study unless the affect could be seen to relate in some way to human health...