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MJ's little flock

10 mg/kg for acetaminophen is what we were talking about unless I missed something.
Ah yes.
Acetaminophen (aka paracetamol) has been found to be safe in birds generally and specifically in chickens (source NIH link below).
Therapeutic doses are 10mg/kg of body weight. Most studies give that intramuscularly and I didn't find a direct dose oral comparison. I imagine if given over several days the same dosage would be appropriate orally.
One study did administration in water using 500mg per liter of drinking water. I personally hate using drinking water methods for dosage because there are too many unknowns about how much the chicken actually drinks.
The range of safety is reasonably broad with fatal toxicity not seen until reaching a dose of 1250mg/kg.
I grew up with the notion that acetaminophen is a dangerous drug because of the nasty effect on failed suicides in people - you wake up and regret your overdose and then 3 days later die from liver failure. Nasty stuff.
But it seems my prejudice is wrongly placed for use in chickens where it appears to be safe and therefore useful in pain and inflammation management.

Here are the sources for the above
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997462/
https://www.tandfonline.com/doi/abs/10.1080/15569543.2021.1974043 (abstract only)
chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/http://www.ijpsrjournal.com/File_Folder/23-26(ijpsr).pdf

Hope that helps.
 
Ah yes.
Acetaminophen (aka paracetamol) has been found to be safe in birds generally and specifically in chickens (source NIH link below).
Therapeutic doses are 10mg/kg of body weight. Most studies give that intramuscularly and I didn't find a direct dose oral comparison. I imagine if given over several days the same dosage would be appropriate orally.
One study did administration in water using 500mg per liter of drinking water. I personally hate using drinking water methods for dosage because there are too many unknowns about how much the chicken actually drinks.
The range of safety is reasonably broad with fatal toxicity not seen until reaching a dose of 1250mg/kg.
I grew up with the notion that acetaminophen is a dangerous drug because of the nasty effect on failed suicides in people - you wake up and regret your overdose and then 3 days later die from liver failure. Nasty stuff.
But it seems my prejudice is wrongly placed for use in chickens where it appears to be safe and therefore useful in pain and inflammation management.

Here are the sources for the above
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997462/
https://www.tandfonline.com/doi/abs/10.1080/15569543.2021.1974043 (abstract only)
chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/http://www.ijpsrjournal.com/File_Folder/23-26(ijpsr).pdf

Hope that helps.
Fantastic. Thank you!

It's very reassuring to know I've been getting the dose right. Although this morning she refused her pain relief. She's too sick to eat a tiny pinch of bread and half a dozen cheese gratings. No poops overnight. She's drinking a lot though. So the linco is definitely getting into her.
 
Joyce ate up her morning ibuprofen while I wasn't watching. She produced a half-solid poop (a vast improvement) but she still looks like she's suffering.

The top one is Joyce's, the bottom one is Christa's.

IMG_2023-05-06-17-05-07-261.jpg

She ate her late afternoon bread and cheese treat with paracetamol very quickly. I switched to paracetamol because I recalled how quickly she ate it the first time. I think she likes the cherry vanilla flavour.

She still looks awful though.

Hopefully that poop is a sign her internal swelling is reducing.
 
Joyce ate up her morning ibuprofen while I wasn't watching. She produced a half-solid poop (a vast improvement) but she still looks like she's suffering.

The top one is Joyce's, the bottom one is Christa's.

View attachment 3494771

She ate her late afternoon bread and cheese treat with paracetamol very quickly. I switched to paracetamol because I recalled how quickly she ate it the first time. I think she likes the cherry vanilla flavour.

She still looks awful though.

Hopefully that poop is a sign her internal swelling is reducing.
That is a good sign. It seems she is eating enough even if it is not a lot. 👍
 

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