Yes, it is very safe and effective. I killed off three colonies in a week with this. I went from Rats taunting me to no rats seen. Very satisfying....Just to put into perspective the following is the amount required to be toxic in various animals.
0.3 to 7 mg/kg in rats,
3.0 to 7.5 mg/kg in dogs,
4.7 mg/kg in cats,
150 mg/kg in pigs,
50 to 300 mg/kg in mice,
35 mg/kg in rabbits
So basically a dog would have to eat a **** load of rats to get the blood levels needed to get sick