I used Tylan 50 injectable only once on a hen 3 days in a row, and that hen is fine. The Tylan literature does say that it can be irritating, and I really would not ever recommend using the Tylan 200 as an injection on chickens, since it is 4 times as concentrated, but some people do use it. Someone on BYC once gave a Tylan injection, and their chicken died immediately--that may have been from an improper injection, or some unusual reaction or severe stress. Since I don't see a sick chicken that often, I haven't used Baytril, but it is a good drug. Bacteria can build up a resistance to antibiotics after time, so I would use Tylan or the other drugs first (oxytetracycline, erythromycin) before using Baytril for every infection. Of course, that is just my opinion, plus the fact that I don't have Baytril.