Unknown Disease Killing My Flock

my flock ranges from my 8 remaining broilers at about 2 months, to my 9 month old birds, about 15 of those, 15 1 1/2 yr old birds from turkeys, ducks and chickens, and some old chickens at about 5-10 who are yard pets, about 6
 
the broilers are about 2 months old. my pullets are about 7 months. my average flock is 1 1/2 yr old. and my chickens that are as old as my home, up to 10 yrs old

but the only ones with symptoms are the pullets and broilers,
with the exception for my guinea
 
the broilers are about 2 months old. my pullets are about 7 months. my average flock is 1 1/2 yr old. and my chickens that are as old as my home, up to 10 yrs old

but the only ones with symptoms are the pullets and broilers,
with the exception for my guinea
The broilers are 2 months old - are you feeding them layer feed? I would correct that and switch to grower, chick starter or a flock raiser type feed. Layer has too much calcium for growing birds.

It very well could be Coccidiosis as mentioned previously, if the broilers have not been with you very long, then I would treat them with Corid.

Are they overheating by any chance? How do you have them housed?
 
You can get Corid at most feed stores or Tractor Supply, it comes in liquid or powder, either will work. Look in the livestock section. I would recommend starting treatment for that (coccidiosis) while you sort it out, it won't hurt anything if something else is going on, but may save your birds if it is what is going on. If it was carried in with any new bird you acquired, then it could be spread from pen to pen on your shoes or any equipment or supplies moved from place to place. You can also give an oral drench of Corid to any birds that are too sick to be drinking well on their own, dosing for that is here, it's given in addition to the medicated water: https://www.backyardchickens.com/threads/corid-oral-drench-instructions.1211991/
Here is the dosing chart for Corid, use the severe outbreak dosing:
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Medicated feed has a very low dose of the same medication in Corid. Medicated feed may prevent coccidiosis , but it will not treat an outbreak, for that you need the full strength dose of Corid. Vitamins should not be given at the same time as the medication as it may reduce the effectiveness of it.
 
Medicated feed will not totally prevent coccidiosis. If you have an outbreak, the Corid in the water is best. If you could get a necropsy done on any that die in the future. It may be a small cost, but it keeps you from medicating or treating for other things. The link back in post 7 is where you can find your state vet. Worming may help as well.
 

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