When I ship out Priority, most packages arrive in 2 days, very few take 3 days, and I'm in Central PA. Cali and the other states way over there are 3 day, but I rarely get a three day package out, they almost always take 2 days. A lot of the time, you can get first classes out in 2 days as well, rarely do they take longer than three days, but there's a weight limit, plus DC is $.10 more per package if you're doing a manual mailing.
As far as packages getting lost, some places just suck. There's nothing more to it than bad employees or something. I've lost one package that was shipped here, which irritates me, because it was a live package, but, other than that one package, I don't remember loosing any others, and I've sent a LOT of packages out. If you sent two to the same place, and they had DC or tracking and were lost, then I'd wait to ship there for awhile, see if something improves. If they were both recent shipments, they could be having some type of problem, like a bad employee or bad roads or something similar.