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The German Shepherd Dog forum has a lot of info their specific growth and don't recommend spaying/neutering until age 2 to make sure they are done growing. I think I'll follow their recommendations for any large dogs. Zeus our Aussie/heeler mix is 50 pounds if he's been hitting the catfood, but we had to wait until he was a year and a half to neuter him, since he broke his leg bad as a 4 month old puppy and the vet wanted as much growth out of the leg as possible. With his temperament, we really didn't need to get him done. He's always been a sweet little cuddle bug.
My Pit/Rott mix had to be fixed around five months old or they would have taken her back.