I have been on Zoloft, it did bad things to me. I switched to Celexa and it got to the point where it was as though I'd built up an immunity to it I suppose. I was on Celexa for 2 years, and it stopped helping. I just got (haven't had a chance to fill a perscription for wellbutrin. THe Zoloft might be great for you, might not. If you notice or friends/family notice something is off, try not to take it personally, but take that info to the dr and see if the dr reccommends a change or not.