avian vet on worming:
(not poultry specific but equally applicable!)
"....I recommend that birds be periodically dewormed, at least once or twice, during routine first examination, with pyrantel pamoate, even if fecal parasite examinations are negative. This is because the gastrointestinal tract transit time is so fast in birds that worm eggs do not concentrate in the fecals (as they do in dogs and cats), and it is not only possible, but likely, to miss ascarids on a fecal exam. I have performed countless second opinions on small birds with GI problems that have had negative tests for worms, yet, when I dewormed them, they passed roundworms! A very interesting paper was published a few years ago about this very problem, out of the University of Georgia. If a bird passes roundworms, it should be periodically dewormed for the rest of its life,
as pathologists have found that larvae may encyst in the tissues and be released during times of stress, resulting in additional worms infesting the intestines...."
http://www.exoticpetvet.net/avian/budgietiel.html
http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/202800.htm
MERCK Veterinary Manual (Worms)
excerpt Piperazine and Fenbendazole:
"Piperazine compounds are relatively nontoxic and widely used against ascariasis. Several piperazine salts are available internationally. Because only the piperazine moiety is efficacious, doses should be calculated based on mg of active piperazine/bird. Piperazine should be completely consumed by birds within a few hours because only relatively high concentrations of the drug eliminate worms. It may be given to chickens as a single dose, 50-100 mg/bird, or at 0.2-0.4% in the feed or at 0.1-0.2% in the drinking water; it may be administered to turkeys at 100 mg/bird <12 wk old, 100-400 mg/bird ¡Ý12 wk old, or in feed or water concentrations as for chickens. Some practitioners recommend the addition of molasses to unmedicated water after piperazine administration, so as to induce an osmotic flushing, theoretically removing any of the remaining worms from the intestinal tract. The medications must also be withdrawn in turkeys 14 days prior to slaughter. There is increasing evidence of significant piperazine resistance in the USA.
Fenbendazole is approved in the USA for use in growing turkeys at the rate of 14.5 g/ton of feed (16 ppm), fed continuously as the sole ration for 6 days for the removal of A dissimilis and Heterakis gallinarum . ..."
When using fenbendazole do NOT over dose and keep in mind:
http://www.avianmedicine.net/ampa/18.pdf
FENBENDAZOLE - Panacur (Hoechst-Roussel)
"....
Fenbendazole should not be used while active feather development is occurring (may damage developing feathers). Has not been found to be effective against the gizzard worm that infects finches.
May not always be effective against capillaria. May be effective
against Syngamus spp. The drug has a low therapeutic index in
some species of finches. A dose of 10 ml/liter of water has been
associated with death three to five days following administration.
This dose may cause ataxia, depression and mydriasis in canaries.
I do not have time to go and pull up all the references but my understanding is to use the ivomec(brandname)EPRINEX and then TOPICALLY (there is a study (avian) which showed the drug is more effective/longlasting (effecacy in the following five weeks following application>mites etc) when topically applied on skin rather than ingested. Some (non-poultry specific) info :
IVERMECTIN - Ivomec, Eqvalen (Merck Agvet)
Supplied as an injectable solution (10 mg/ml) for IM, topical or oral
administration. Effective for some nematodes, mites and lice. Most
effective therapy for Knemidokoptes. Calculated dose can be used
topically on affected areas or can be given orally. May also be effective for Oxyspirura, some coccidia, some nema-
todes, gapeworms and sternostamatosis. May not be effective
against all coccidia. Toxic in bullfinches and goldfinches when used
topically at 0.4 mg/kg. Propylene glycol is used as a carrier in the
solution designed for cattle and pig use.
This product will precipi-
tate out if diluted with sterile water. The propylene glycol-based
product may cause toxic reactions when administered IM, particularly in small birds. Ivermectin diluted in propylene glycol will
settle out and the diluted product should be thoroughly mixed
before administration. The water-soluble preparation designed for
use in horses is easier to work with and appears to be safer.
However, deaths in finches and budgerigars have been reported
when Eqvalan (the water based formula) was administered IM at
the recommended dose.Ivermectin is environmentally stable and is highly toxic to fish and crustaceans. The drug or its metabolites should not be allowed to contaminate lakes, streams or rivers."
>>>do NOT use fendazole on young feather developing age birds nor on molting birds!