I have a 04 Ford F350,  which I love!  except the auto locking. LOL 
I dont mind it unless I go somewhere alone, pull up to the house, get out adn go in- THEN, run back out later to get something out of the back seat or passenger side door and the durn thing is locked. LOL 
This one did take some getting used to,  I had power locks on my 89,  but no 'smarter than you' features. 
One thing that I have learned to do. 
get an extra key made-  leave it in the ignition at ALL times.  
Then use your clicker to lock and unlock the doors.  
of course with mine (and this baffled me for over an hour one day- seriously)  with mine, if you have a key in the ignition, and you hit the lock button, when you shut the door it unlocks itself. it refuses to allow you to lock your keys in your truck.    the only way to lock the truck with keys in the ignition is with a fob.  you can even lock it running that way- which is great for me, I drive a deisel, and prefer to keep it running on a quick trip into the store, or  if I have milk and such in 100plus heat. 
when I lost my key fob, I still keep that key in my truck, NEVER taking it out of the truck.  I do have to take it out of the ignition, since I cant automatically lock it with the fob anymore. (I need to buy a new one)-  I put it in the ashtray,  then I lock the doors, shut them and get in through the keypad.  
But, even before I had a fob thing, back to when I was 16, I kept 2 keys. ONE stayed IN my purse, it was ONLY used to unlock the doors.  it went right back in my purse. The other stayed IN the ignition.  (and at least one, usually two are always stuck under my bumpers. because I loose keys ALL the time. )- I might be locked OUT, but there is always an extra key IN the truck, so I can drive off after I get in. (even if I have to break a window to get in....  I can still drive off.. LOL )  Two things made me do this:    I learned my lesson after someone had my keys  out of town for 4 days and I couldnt even leave my own home.  They accidentally took them, but still. 
and once I swore my keys were lost IN the car, like between the seats, doors locked, everything, so I broke a window.   come to find out, they were NOT in the car, and I missed school anyway.  
  And I've heard of people being hours away from home and having to get the keys brought to them cause they locked them in the car and couldnt get or afford a locksmith.   
I have always had a car since I was 16 that had automatic locks (a 79 Toyota, 89 F350 and 04F350)-  This is the first time I have ever had a fob.  I WORSHIP my fob. LOL  and I really cant wait until I can afford a new one.    I love being able to unlock the doors from a distance.   But aside from that, even just the fact that I dont have to walk around and lock all the doors is wonderful for me. Especially with kids.   Hubbys truck is non automatic,  and its a pITA.