from this link:
http://npic.orst.edu/factsheets/cuso4tech.html
"Adult roosters were exposed by intubation to copper sulfate doses of 200, 600, 800, 1200 and 1600 mg/kg body weight. The acute LD50 was determined to be 693 mg/kg. Treated animals developed diarrhea and died within 24 to 28 hours. Necropsies revealed bleeding of the kidneys and liver, necrosis in liver tissue, and testicular atrophy."
"Newly hatched white leghorn chicks were orally dosed with copper sulfate at a concentration of 10 mg/kg body weight. Chicks were sacrificed after 24 hours, and bone marrow chromosome aberration tests demonstrated an increased incidence of micronuclei in exposed chicks, indicating DNA damage.
51"
"Adult chickens were exposed to copper sulfate by gavage at concentrations of 200, 600, 800, 1200, and 1600 mg/kg body weight. Researchers noted testicular atrophy and spermatogenic arrest proportional to the concentrations of copper sulfate.18"
"
Researchers fed 450 mg/kg copper from copper sulfate to male chicks for 21 days. They noted reduced feeding and less weight gain in exposed birds.40"
from this link:
http://msucares.com/poultry/diseases/solutions.html
"COPPER SULFATE SOLUTION
Use this solution as a treatment for mycosis (mold infection) in the crop. An alternate name for the condition is "Thrush." Use the solution as a "follow-up" treatment after flushing with epsom salt solution--refer to the section for LAXATIVE SOLUTIONS.
Dissolve .5 lb copper sulfate and .5 cup vinegar into 1 gallon of water for a "stock" solution. Dispense stock solution at the rate of 1 oz per gallon for the final drinking solution.
An alternate method of preparing the solution is:
dissolve 1 oz copper sulfate and 1 tablespoon of vinegar into 15 gallons water.
Use either solution as the sole water source during the course of the disease outbreak. Copper sulfate is often referred to as "bluestone"."
"Epsom Salt Solution
1 lb Epsom Salt per 15 lb feed
-or-
1 lb Epsom Salt per 5 gallons water for 1 day
Give the epson salt feed mixture as the sole feed source for a one day period. This feed can be used only if the birds are eating. If the birds are not eating, use the water solution. If the birds are unable to eat or drink by themselves, use individual treatment with:
1 teaspoon of Epsom Salt in 1 fl oz water
Place the solution in the crop of the affected bird. This same amount of solution will treat 5-8 quail or one chicken."