Coronavirus, Covid 19 Discussion and How It Has Affected Your Daily Life Chat Thread

[Brooks_]

I guess it depends upon the issue. Grand daughter has Lupus and her specialists highly recommended that she get the vaccine.

I'm sorry. The scarring can be bad.

 

[Molpet]

That's not actually true, the drugs are actually different. and Ivermectin has been in trials, and didn't make a difference in patient outcomes.
Also, the whole thing started because in test tubes, at 100x the human dose, it killed C-19 virus. Nice, but 100x the human dose in a test tube isn't helpful in real patients at safe dosages. It's great drug if you have roundworms, but for viruses, not so much.
Mary

Oxford is doing an ivermectin trial.
https://www.clinicaltrialsarena.com/news/ivermectin-principle-trial-covid/

 

[Brooks_]

Oxford is doing an ivermectin trial.

Designed to fail. Big pharma will not allow off patent treatment.

 

[Folly's place]

Good, actual studies and trials are good. Much better than at-home experiments!
Mary

 

[EmmaDonovan]

That's not actually true, the drugs are actually different. and Ivermectin has been in trials, and didn't make a difference in patient outcomes.
Also, the whole thing started because in test tubes, at 100x the human dose, it killed C-19 virus. Nice, but 100x the human dose in a test tube isn't helpful in real patients at safe dosages. It's great drug if you have roundworms, but for viruses, not so much.
Mary

Ivermectin doesn't "kill" the SARS-CoV-2 virus. Ivermectin binds to the SARS-CoV-2 spike protein, limiting SARS-CoV-2 binding to either the ACE-2 receptor or sialic acid receptors. This either prevents cellular entry of the virus or prevents hemagglutination, respectively.

Ivermectin has also been shown to bind to or interfere with multiple essential structural and non-structural proteins required by the virus in order to replicate. Ivermectin also binds to the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp), thereby inhibiting viral replication.

The source studies are listed at the bottom of this pdf document.

As far as dosage, I agree that the concentrations required for effect in cell culture models bear little resemblance to human physiology given the absence of an active immune system working synergistically with a therapeutic agent such as Ivermectin. Prolonged durations of exposure to a drug likely would require a fraction of the dosing used in short term cell model exposure. I don't know what amount "100x the human dose" is. The minimum recommended treatment protocol for someone 150 lbs. (dosing is based on weight) is approximately 27mg, once a day for five days.

 

[EmmaDonovan]

Good, actual studies and trials are good. Much better than at-home experiments!
Mary

I agree. Clinical studies on the efficacy of ivermectin in treating mildly ill outpatients, clinical studies of the efficacy of ivermectin in hospitalized patients, Ivermectin's use in post-COVID-19 syndrome, and epidemiological data showing impacts of widespread Ivermectin use on population case counts and case fatality rates can be found here.

That's some good reading.

 

[Hayden Goseek]

I spoke to a ultrasound tech today after he had measured the heart of a Covid patient. I asked if they were finding a lot of damage from the virus. He said "Yes. Especially in the unvaccinated ones."

 

[Brooks_]

I spoke to a ultrasound tech today after he had measured the heart of a Covid patient. I asked if they were finding a lot of damage from the virus. He said "Yes. Especially in the unvaccinated ones."

Yet, myocarditis has been linked to the vaccine.

 

[Hayden Goseek]

Yet, myocarditis has been linked to the vaccine.

I understand but linked is a vague word. This fellow was hiking in Colorado last week and has a 55% ejection fraction this week.

 

[Brooks_]

I understand but linked is a vague word

I'll not link as I think you know what I meant.

a 55% ejection fraction this week.

I don't know what that means,