Mareks disease can have many different symptoms. There are 4 types-- the type that affects the nerves which may cause weakness or paralysis in one or both legs or wings; the type that causes tumors in internal organs; one that causes skin lesions and tumors; and the type that can cause eye color changes, pupil size changes, and blindness. Sometimes you may only see one type or symptom. It can cause subtle changes or sudden paralysis and death. Some will eat readily, while others starve themselves. It can take some time to watch her. Some get better, only later to get worse.