Yes... and no. One of my brooders has a standard 75W bulb, but it's inside away from drafts, and the bulb hangs pretty low in the cage - almost ON them.
With a 250W bulb, you have to remember two things. First, make sure it is secure so it doesn't fall and burn/melt anything. Second, give the babies enough room to move away from it. They will regulate their own temperature in that situation - move under the lamp when they are too cold, and move away when they are too warm.
If you go with a normal 75W or 100W bulb, make sure it's still in a silver dome fixture, and that all of the babies can fit under it. If you have too many babies for it, either set up another fixture, or use the 250W bulb.
The one big disadvantage to the 250W bulb, is how fragile they become once they warm up. The heat from them (at least in a dome fixture) makes it very easy for the glass to separate from the metal base. When that happens, the bulb is left hanging from the fixture by two thin wires. And moving those when hot can result in an incomplete circuit, and thus a bulb that doesn't work. I've gone through COUNTLESS bulbs that way (which is why I have a normal bulb, since TSC can't keep heat bulbs stocked this time of year). A simple bump of the fixture is enough to knock the glass out of the metal base, too.
Just imagine trying to unscrew the metal base out of a light socket, because a bulb busted, to understand the trouble it causes!