In the end? It comes down to experience.
We never, ever had coccidiosis here. Ever.
Then? This spring was horribly slow in coming. Wet, cool and odd. Wouldn't you know it, we had cocci outbreak for the very first time. There are, as you know, 8 or 9 strains, so it isn't just ONE thing. They morph. They adapt. They change and they are carried about the planet by migrating birds. The stuff this early summer in the northlands, here and right on up through eastern Canada was VIRULENT. Deadly as all get out. The strain went right through medicated feed like it was a joke. I'll never buy medicated feed again. Waste of time.
Corid water. 1/3 to 1/2 teaspoon per gallon. Knocks it out NOW, but the chicks have to actually drink it. Droppers are sometimes necessary if the situation is dire. I wouldn't worry about whether it is this micro difference in the formulas. Come on. Just put 1/2 teaspoon of the 20% powder and get it into your birds or they die. It's that simple. Some of these strains kill so fast that while I'm scratching head over meaningless differentials in precise dosing, I've lost 20 chicks, bled out and dead, and often these are irreplaceable, rare, heritage, breeder chicks.
Yogurt or raw milk, straight from the goat or cow is also soothing. NO VITAMINS during treatment. You're working against the med. Corid ie, amprolium, works by starving thiamine from the cysts in the gut. Don't feed the cysts vitamins, for heaven's sake. Serve corid water for 8 days. Take a week off and if you're even the least bit concerned, run them through a second 6 days of follow up. Amprolium is fairly innocuous to the bird. It's not an anti-biotic. You can even feed amprolium in small doses to hens and eat their eggs. I don't, but it shows how relatively innocuous Corid is.
No offense intended by my rather "forth right" talk here, but I'm a wee bit sensitive. I lost some irreplaceable chicks to death so I'm not particularly in any mood to use my more politically correct tone here.