Oh no, I have made a BIG mistake. HELP

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unbaked pegga

unbaked pegga

Songster
9 Years
Nov 22, 2014
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Lebanon TN
I have a 3 month old chick that has been doing poorly. I Was giving her Tylan .3 mL because she is so small. I could not find the syringe I normally use. So I got another one and I drew up the wrong amount! Instead of .3 mL I gave 3 mL. Oh my God have I killed her?
 
Interestingly enough, the document I found literally said to not give Tylan to chickens. But we all know that it is done. Here is some info for you.

"Overdose (symptoms, emergency procedures, antidotes), if necessary
Pigs and calves: Intramuscular injection of 30mg/kg bodyweight per day (three times maximum recommended dose) for five days produced no adverse effects.
The LD50 for subcutaneous injection of tylosin in mice is estimated to be >2500mg/kg bodyweight."
 
How much active ingredient is in 3 ml? Is it the 50mg per ml liquid concentration? If so, you dosed 150mg. Did you have the bird drink it, or did you inject it? I think you are probably ok either way......

Non-Human Toxicity Values:
LD50 Mouse oral 10 g/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 3637] **PEER REVIEWED**

LD50 Mouse Intraperitoneal 594 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 3637] **PEER REVIEWED**

LD50 Mouse iv 400 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 3637] **PEER REVIEWED**

LD50 Dog oral >800 mg/kg bw
[WHO/FAO; Seventieth Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA); Toxicological Evaluation of Certain Veterinary Drug Residues in Food, WHO Food Additive Series 61: Tylosin p.190 (2009). Available from, as of October 16, 2015: http://www.inchem.org/pages/jecfa.html **PEER REVIEWED**

LD50 Rat oral >5,000 mg/kg bw
[WHO/FAO; Seventieth Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA); Toxicological Evaluation of Certain Veterinary Drug Residues in Food, WHO Food Additive Series 61: Tylosin p.190 (2009). Available from, as of October 16, 2015: http://www.inchem.org/pages/jecfa.html **PEER REVIEWED**
 
Last edited:
paneubert said:
Interestingly enough, the document I found literally said to not give Tylan to chickens. But we all know that it is done. Here is some info for you.

"Overdose (symptoms, emergency procedures, antidotes), if necessary
Pigs and calves: Intramuscular injection of 30mg/kg bodyweight per day (three times maximum recommended dose) for five days produced no adverse effects.
The LD50 for subcutaneous injection of tylosin in mice is estimated to be >2500mg/kg bodyweight."
Click to expand...
I gave it orally not IM That is probably worse. I have never been in such a state. I called the vet and I have a 3 month old chick that has been doing poorly. I Was giving her Thailand .3 mL because she is so small. I could not find the syringe I normally use. So I got another one and I threw up the wrong amount! Instead of .3 mL I gave 3 mL. Oh my God have I killed her
paneubert said:
Interestingly enough, the document I found literally said to not give Tylan to chickens. But we all know that it is done. Here is some info for you.

"Overdose (symptoms, emergency procedures, antidotes), if necessary
Pigs and calves: Intramuscular injection of 30mg/kg bodyweight per day (three times maximum recommended dose) for five days produced no adverse effects.
The LD50 for subcutaneous injection of tylosin in mice is estimated to be >2500mg/kg bodyweight."
Click to expand...
oh I gave it orally not IM. I am sure that makes it worse. I called the vet and he said she might die but he probably thought I gave it IM too. I am in such a state
 
I think oral is not as bad actually. According to those stats at least. Takes a hell of a lot to kill a rat it seems. And still a lot more than what you gave to kill a dog. Also, the LD50 only means it killed 50% of the animals. So even if you hit the unknown LD50 for chickens, there is still a 50/50 chance the bird will survive.
 
paneubert said:
How much active ingredient is in 3 ml? Is it the 50mg per ml liquid concentration? If so, you dosed 150mg. Did you have the bird drink it, or did you inject it? I think you are probably ok either way......

Non-Human Toxicity Values:
LD50 Mouse oral 10 g/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 3637] **PEER REVIEWED**

LD50 Mouse Intraperitoneal 594 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 3637] **PEER REVIEWED**

LD50 Mouse iv 400 mg/kg
[Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 3637] **PEER REVIEWED**

LD50 Dog oral >800 mg/kg bw
[WHO/FAO; Seventieth Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA); Toxicological Evaluation of Certain Veterinary Drug Residues in Food, WHO Food Additive Series 61: Tylosin p.190 (2009). Available from, as of October 16, 2015: http://www.inchem.org/pages/jecfa.html **PEER REVIEWED**

LD50 Rat oral >5,000 mg/kg bw
[WHO/FAO; Seventieth Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA); Toxicological Evaluation of Certain Veterinary Drug Residues in Food, WHO Food Additive Series 61: Tylosin p.190 (2009). Available from, as of October 16, 2015: http://www.inchem.org/pages/jecfa.html **PEER REVIEWED**
Click to expand...
oh I gave it orally which is probably worse. It is Tylan 50 and there is 50 mg in a cc. She is so frail anyway. Probably maybe 1.5 kilo’s About half the size of the other 2 chickens that are the same age. I am a nurse and I can’t believe I made such a glaring error. If I killed her I will never forgive myself
 

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