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Congrats! I was sick from week 6 to week 18 and Zofran is like a miracle drug! I still felt a little nauseous with it, but was able to function and go to work. Without it I would have been in trouble.
I had hyperemesis with my first 2 pregnancies and Zofran is wonderful! I was vomiting from 7-35 weeks with both of them and Zofran kept me from vomiting as much, but I did still feel nauseous a lot.
I took it with my 3rd baby, too. I would take it when I felt nauseous and I never threw up.
I didn't feel sick at all with this 4th one and didn't need any anti-nausea drugs.
It's an expenisive drug, although I hear they have a generic version out now that wasn't available during my first pregnancies. It also causes constipation, so watch out for that.