Levamisole wormer info needed

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Even though it's not labeled for use in chickens here in the US, I thought you might find this egg and meat residue study interesting.
https://www.ncbi.nlm.nih.gov/pubmed/15685936
Levamisole residues in chicken tissues and eggs.
El-Kholy H1, Kemppainen BW.
Author information

Abstract
Levamisole is currently being used to treat capillaria infection in chickens even though there is no published withdrawal information available for levamisole in chickens. Tissue residue withdrawal of levamisole in chickens was studied in 32 healthy broiler breeder chickens at the age of 32 wk (peak of egg production). Levamisole residues in chicken tissues, eggs, and plasma were determined by HPLC with ultraviolet (UV) detection at 225 nm. The highest level of residue and longest withdrawal after oral administration of 40 mg/kg levamisole to chickens was in the liver. On d 3 the level of levamisole were undetectable in the plasma. On d 9, levamisole residue in eggs was 0.096 microg/g and on d 18 it was 0.06 microg/g or less in all the analyzed chicken tissues. Those levels were lower than the recommended maximum residue limit (MRL). The withdrawal time for levamisole in chickens was longer than for other species tested, which is due in part to a larger dose of levamisole being recommended for chickens. In conclusion from this research, 9 d are needed for levamisole in eggs to be less than the MRL, and 18 d of withdrawal are needed before medicated birds are slaughtered if their tissues are to be safe for human consumption.
 
casportpony said:
Even though it's not labeled for use in chickens here in the US, I thought you might find this egg and meat residue study interesting.
https://www.ncbi.nlm.nih.gov/pubmed/15685936
Levamisole residues in chicken tissues and eggs.
El-Kholy H1, Kemppainen BW.
Author information

Abstract
Levamisole is currently being used to treat capillaria infection in chickens even though there is no published withdrawal information available for levamisole in chickens. Tissue residue withdrawal of levamisole in chickens was studied in 32 healthy broiler breeder chickens at the age of 32 wk (peak of egg production). Levamisole residues in chicken tissues, eggs, and plasma were determined by HPLC with ultraviolet (UV) detection at 225 nm. The highest level of residue and longest withdrawal after oral administration of 40 mg/kg levamisole to chickens was in the liver. On d 3 the level of levamisole were undetectable in the plasma. On d 9, levamisole residue in eggs was 0.096 microg/g and on d 18 it was 0.06 microg/g or less in all the analyzed chicken tissues. Those levels were lower than the recommended maximum residue limit (MRL). The withdrawal time for levamisole in chickens was longer than for other species tested, which is due in part to a larger dose of levamisole being recommended for chickens. In conclusion from this research, 9 d are needed for levamisole in eggs to be less than the MRL, and 18 d of withdrawal are needed before medicated birds are slaughtered if their tissues are to be safe for human consumption.
Click to expand...

Thanks Kathy! I am always interested in knowing what I am putting in their bodies and how long it resides in the tissues. Good stuff!
 
casportpony said:
Wow, that seems like a lot. Can you consult with your vet?
Click to expand...

As potent as this stuff is, I have to agree, using this for 3 to 7 days along with high doses sounds like a lot. I will keep researching and also talk to my Vet's assistant, she is the resident poultry expert at the clinic. I will let you know when I learn something on this! :)
 

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