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Our mutt dog weighs about 40 pounds I believe. My daughter just used Ivermectin pour on (blue liquid) on him. She had a syringe with about 1/4 cc liquid in it, and used most of it (drops on his neck). He is still alive and well. Maybe she just got lucky, I don't know.
Sorry, I made an assumption I shouldn't have. Because we have been talking about the oral dose I assumed you meant giving pour on orally. By actually pouring it on you have to rely on the animals ability to absorb it in to there system threw the skin. Even in cows its 5 times stronger to make this work. In horses it is known to make it to the bloodstream but is usually not very effective at the levels that make it there. The studys that I saw with dogs seem to show that its so inefficient that the odds of curing anything in a dog with the pour on is almost zero. Hartworm was not part of there test though.
Back to the 1% injectable taken orally....
To give you an idea of what you are paying for with hartguard, its dosing for just hartworm is actually:
10 lbs = .0027 cc or ml
20 lbs = .0055 cc or ml
30 lbs = .0082 cc or ml
40 lbs = .011 cc or ml
50 lbs = .013 cc or ml
60 lbs = .016 cc or ml
70 lbs = .019 cc or ml
80 lbs = .022 cc or ml
90 lbs = .025 cc or ml
100 lbs = .027 cc or ml
breeders treating for mange, mites, worms, exc dose at 1/10th ml or 1/10th cc or 10 units of a insulin needle for every 10 pounds.
Besides the herding dog warning, abluechipstock's warning about not going over .8ml or .8cc or 80 insulin units is sound advice. I have heard that warning many times so I assume it is true.