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Denagard is very bitter, and I get the impression that it is somewhat irritating to the mouth and crop if given undiluted. Therefore, it is best to dilute the medication in food or water, and give small portions of the total daily dose over the course of the day, not the total dose all at once. If you can get the birds to eat it, maybe mix it with some honey or syrup to sweeten the taste, then give 1/3 of the total amount at a time, mixed in food. Repeat three times every day, so that the total daily dose is given over 24 hours.
The most commonly recommended dose is 25-50 mg/kg over 24 hours.
If you had a 2.5 kg (5.5 pound) bird, the daily dose would be 62.5-125 mg. (2.5 kg X 25-50 mg/kg = 62.5-125 mg)
The medication comes in a 12.5% oral liquid. That's the equivalent of 125 mg/ml (or cc if you prefer, as ml and cc are the same thing).
Therefore, you would give a 5.5 pound bird 0.5 to 1.0 ml over the course of the day. (62.5-125 mg divided by 125 mg/ml = 0.5-1 ml)
From a practical standpoint, I would go with a middle range dose, which would be 0.75 ml total. I would put 0.25 ml of Denagard in a one ml syringe, pull up an additional 0.25-0.5 ml of honey or syrup, mix thoroughly in the syringe, then mix that with 1-2 tablespoons of grain or cooked rice in a small bowl, or soak it up in a several bite sized pieces of bread. If they ate that well, I would repeat that three times a day.
If your bird is smaller or larger than 5.5 pounds, here's how you figure out how much to give:
1) Weigh your bird. If you weigh it in pounds, then convert to kg by dividing pounds by 2.2. Example: 4.2 lbs divided by 2.2 = 1.9 kg
If you can't weigh your bird you won't be able to dose it accurately. If you can estimate weight fairly well, then using a mid-range
dose is probably safe.
2) Multiply the kg weight by the dosage, or the dosage range. Example: 1.9 kg X 25-50 mg/kg = 47.5 - 95 mg
Or if you want a mid-range dose (37.5 mg/kg) instead of a dose range: 1.9 kg X 37.5 mg/kg = 71.25 mg
3) Divide the concentration of the medication (125 mg/ml) by the number of mg needed. Example: 71.25mg divided by 125 mg/ml = 0.57ml
Or if you want a range of options: 47.5 - 95 mg divided by 125 mg/ml = 0.38 - 0.76 ml
4) Divide the total daily ml by the number of times per day you plan on giving the medication. Example: 0.57 ml divided by 3 times per
day = 0.19 ml Denagard given three times daily. Then add honey or syrup and add to food. If you need to syringe it directly into the mouth because
the bird won't eat the medicated food, you might want to dilute it out further with water, and ideally give it when there is already food in the crop, if
possible.