I think the more they are exposed the better they can adapt. I keep mine in my office in a large dog kennel, with the top open (wire across to prevent escaping) and a wire door on one side so they can see us. We've had this set since day one, and they still run around like we are going to kill them when we walk over, but I think that's more just "I'm a prey animal" type reaction. We hold them several times a day, and give them treats. We let them roam on the floor and now outside a bit (I have 3, they are 3 and 4 weeks) and they really like that. They still run when we try to pick them up, but settle quickly. Our dog stays behind gates but can get close enough to sniff them, and they certainly hear her barking, and us talking all day. One nice thing about this isolation is my daughter is always home and gets to spend a lot of time with them. Normally she is in school most of the day and misses them. Just keep holding and offering treats. They will get used to you but remember, they are a prey animal, so instinct will win out for a while.