Vitamins D and K play roles in immune function and exhibit anti-inflammatory properties, with emerging research highlighting their potential to support immune responses and help manage inflammation. Vitamin K, particularly K2, has been found to influence T-cell-mediated immune responses and may have a role in modulating conditions characterized by inflammation. In studies, Vitamin K2 has shown specific immunomodulatory activities, including the suppression of T-cell proliferation, which is not observed with Vitamin K1.
Vitamin D has been increasingly recognized for its impact on the immune system. It aids in supporting the body's defense against bacteria and viruses and has been found to help manage pro-inflammatory cytokines while enhancing the function of immune cells. For example, lower levels of Vitamins D and K have been observed in patients with inflammatory conditions. Additionally, Vitamin D is reported to help manage the activity of dendritic and T cells, playing a role in reducing inflammation.
Recent studies have linked low levels of Vitamin D with an increased risk of autoimmune and chronic conditions, suggesting that maintaining adequate levels of these vitamins is important for overall health. While the exact mechanisms of how Vitamins D and K work in immune function and inflammation are still being explored, overall, the research indicates a significant role in modulating immune responses and potentially helping manage inflammation-related conditions (4,24).
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