For all of you that advocate the .22 RF for varmint, there is a tool that might appeal to you. It is made by a guy named Paco Kelly and it is nothing more than an old fashioned swaging/reforming tool. These were not uncommon back in the old days when most cartridges had heel-based bullets.
Essentially they swage (squeeze form) the bullet to a consistent diameter; their original intent was to generate more consistent accuracy from budget factory ammo.
BUT Paco's tool also modifies the tip of the bullet. You can get anything from a mild wadcutter shape to a full blown NastiNose hollow point from them. Its safe to say they give more "thump," to what is essentially a fairly anemic round to start with.
They especially shine when it comes to the cheaper, lower velocity ammo.
One of the reasons we love the .22 is for it's low price; "buck a box" standard and high velocity stuff is available almost everywhere, even today in gun-a-phobe America. There are four general velocity ranges for .22 LR ammo
Subsonic velocity - below 1,080 ft/s
Standard velocity - slightly supersonic muzzle velocity, around 1,125 ft/s1
High Velocity - 1,200 ft/s to 1,300 ft/s
Hyper Velocity - 1,400 ft/s to 1,800 ft/s
Normally the hypers use lighter bullets as a method to achieve their high velocities
The down side is that the cheaper ammo is usually loaded with round nose bullets, or ineffective hollow points, neither of which do all that much at the terminal point.
They also are not made to be match grade accurate.
But Paco's tool changes all that; by reforming the size to a consistent measure, you get better shot-to-shot accuracy.
Then, by reshaping the nose (the ogive) to a blunt and/or open profile, they give a terminal effect out of proportion to their velocity. So you get better accuracy and terminal performance.
I like to use the tool on subsonic and standard velocity .22's, in particular. But, you can use it on any of them and when used on the hyper velocity fodder, well... they become something much 'meaner'. I wouldn't consider shooting a coyote with anything else. Well... I wouldn't consider it with these either, but it's a start.
The tools aren't cheap, I think I paid $35 for mine some years ago. But they are simple, well made and will last a life time. You can learn about them here:
http://www.gunblast.com/Paco2.htm