It’s progresses to an aggressive histamine reaction - the venom causes a release of a chemical called histamine which causes swelling and itching. But it can spread if you have a severe reaction to the venom or as in my case a delayed reaction.Would vinegar of baking soda help.
I've had so many bites this year
I can leave it and it will resolve eventually but as I keep scratching it I could get a skin infection from scratching (cellulitis), not to mention walking is itchy and painful with the swollen areas rubbing on my shoe. And antihistamine is the fastest way to get the swelling down.
Darn Yellow Jackets

Scratching the surface tax
Curly Fluffy Butt